The Use Of Testosterone To Remediate Osteoporosis In Men

Normal bones in comparison to the bones of patients with Osteoporosis

Osteoporosis is a very common bone disease that is caused by the loss of bone density. Osteoporosis means “porous bone”, and results in the bone becoming weak and brittle in some serious cases. The loss of bone density or mass causes the bone to have abnormal tissue structure. Studies have shown that up to one in four men age 50 and older will break a bone due to osteoporosis. Breaking bones is very serious as osteoporotic bone breaks are most likely to occur in the hip, spine, or wrist. It can also lead to some patients to lose height or cause a stooped or hunched posture. Osteoporosis may limit mobility in patients which often prompts isolation and depression. Although, osteoporosis is not considered a life-threatening disease, older patients who sustain a broken bone often suffer from long term complications related to it or require long term nursing home care. Symptoms of osteoporosis include:

Some risk factors for osteoporosis include women after menopause, men and women over the age of 50, higher body mass index or men and women with smaller body frames, family history of osteoporosis, white or Asian descent. Other factors such as diet, medication, lifestyle, and hormonal issues can also contribute to a higher risk of osteoporosis. Eating disorders and low calcium intake for a long time can diminish bone density in both men and women. Prescription medications for cancer, gastric reflux, seizures, and transplant rejection have also been associated with osteoporosis. People with celiac disease, inflammatory bowel syndrome, kidney or liver issues, multiple myeloma, lupus, or rheumatoid disease are at a higher risk for osteoporosis. Excessive alcohol consumption, tobacco use, and a sedentary lifestyle also have a higher risk of patients for osteoporosis. Hormonal imbalance is the other cause of this disease. Lowered sex hormone levels with aging cause weakened bones. In men, a gradual reduction in testosterone levels with aging is one of the most important cues that researchers picked up to treat osteoporosis. 


Testosterone has a direct effect on bone health. Testosterone deficiency can be caused by age, prostate cancer treatment, glucocorticoids, or hypogonadism. Testosterone is a hormone associated with male sex drive found in both men and women. Including fluid retention, decreased sexual dysfunctions, depression, low levels of testosterone can also aid osteoporosis. Testosterone signaling stimulates osteoblasts, a type of bone cells, to form bone and helps osteocytes prevent bone loss. Although, the detailed role of testosterone in bone health of elderly men is less clear and likely reduces fracture risk. 


Testosterone replacement therapy, or TRT, is a hormone replacement therapy for men with low testosterone. TRT is used by physicians to treat a wide range of conditions that are caused by lowered testosterone levels, such as osteoporosis, decreased sexual dysfunctions, and metabolic dysfunctions. According to the US National Library of Medicine, testosterone replacement therapy can effectively reverse bone loss in men as testosterone signaling through a particular receptor in the body promotes bone formation in osteoblasts (bone cells) and inhibits bone loss.


If you have further questions about testosterone therapy or want to schedule an appointment, call our office at (609) 587-9944 or e-mail us at



Anuva Nabiha Anuva is a Boston University undergraduate studying neuroscience in the premedical track. She believes in the importance of mental health in the healthcare system and wants to focus on overcoming the bias against BIPOC in medical science.

You Might Also Enjoy...

Facial Volume Loss

With age the skin worsens and there is noticeable facial volume loss. Luckily, there are numerous types of treatments for improving facial volume, some of which include Dermal fillers and polydioxanone (PDO) threads

Carbon Dioxide Laser Treatment

Regardless of the season the sun is always beaming down on us, so it is important to know about the effect that UV exposure has on the skin. One of the most popular laser treatments to improve the condition of the skin is the carbon dioxide (CO2) laser


Hydrofacial, also known as hydrodermabrasion, is a technique for improving skin condition. There is also Microdermabrasion which works by sanding off the outer layer of the skin and suctioning out dead cells using a vacuum which exfoliates the skin

LED Therapy

LED therapy can be used for many things, some of which include regenerating tissue, and even improving the complexion of your skin. Red, blue, and infrared light were tested in clinical trials and found to help acne, psoriasis, basic skin cancers, etc..

Cavitation Liposuction

While diet and exercise is helpful to achieving the ideal healthy body, there’s some fat that remains no matter how much you try, and Cavitation liposuction can help with ensuring that the stubborn fat stays away

Hair Loss Options

Hair loss can be seen in both men and women for various reasons. It can occur as a complication of another medical condition, hormone imbalance, and from genetics. One helpful treatment is PRP which can stimulate the hair to grow